TOP PHARM CO.,LIMITED
|Place of Origin:||China|
|Brand Name:||Top Pharm|
|Minimum Order Quantity:||10g|
|Packaging Details:||As your requirments|
|Delivery Time:||3-6 working days|
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|Supply Ability:||bulk stock|
|Appearance:||White Loose Lyophilized Powder.||Purity:||99%|
17 Alpha Methyltestosterone,
Muscle Gain 17 Alpha Methyltestosterone,
CAS 58-18-4 17 17 Alpha Methyltestosterone
Alias 17beta-hydroxy-17alpha-methylandrost-4-en-3-one; Mesterone; Andrometh; 17-Methyl Testosterone; Nu-man; Testoviron
CAS No. 58-18-4
Appearance white crystalline powder
Use It is used as a feed additive to produce predominately male populations of tilapia
2. Product description
Molecular Fomula C20H30O2
Molecular Weight 302.45
Purity 99% min.
Character White crystalline powder, odorless, tasteless, hygroscopic, light case of deterioration. Ethanol solution at 240nm wavelength of maximum absorption. Soluble in chloroform and dioxane, soluble in ethanol (1 5), acetone (1 10), methanol, slightly soluble in ether, insoluble in water, vegetable oil. MP 161-166° C, refractive index +69-+75° .
Methyltestosterone is a steroid hormone from the androgen and is found in mammals and other vertebrates, Methyltestosterone is primarily secreted in the tests of mails and the ovaries of female, although small amount are also secreted by the adrenal glands, Methyltestosterone is the principle male sex hormone and an anabolic steroid. Methyltestosterone plays a key role in the development of male reproductive tissue such as the testis and prostates. In addition, Methyltestosterone is essential for health and well-being as well as the prevention of osteoporosis, Methyltestosterone is conserved through most vertebrates, although fish make a slightly difference from called 11-ketotestosterone.
Application For androgen and Albumen Assimilation steriod
The 17 alpha methyltestosterone (MT) hormone is fed to Oreochromis niloticus larvae in fish farms with the purpose of inducing sex reversal. The aim of this study was to evaluate the toxicity and sub-lethality of MT (99.9% purity) and cMT (a commercial MT with 90% purity) in zebrafish (Danio rerio) adults, where the animals were exposed to concentrations of 0, 4, 23, 139, 833 and 5000 µg/L for 96 hours. Genotoxicity was evaluated by micronucleus test (MN), nuclear abnormalities (NA) and comet assay. A low genotoxic potential of MT was showed, inducing micronucleus, nuclear abnormalities and DNA damage in Danio rerio, depending on the use of MT or cMT, gender and tested concentrations. In the sub-lethality trials, there was a basal difference in the activity of the enzymatic biochemical markers for males and females, while the Glutatione S transferase (GST) activity decreased in all analyzed tissues, and for males the enzymatic activity decreased only in the intestine. Results suggest that MT has a toxic potential to fish because it alters enzymatic metabolic pathways and may pose a risk to the ecosystems.
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