I
Product Name Oxytocin Acetate
Sequence
Cas No. 50-56-6
Molecular Formula C43H66N12O12S2
Molecular Weight 1007.2
Purity (HPLC) 98.0%min.
Appearance? White powder
Single Impurity(HPLC)? 1.0%max
Amino Acid Composition? ±10% of theoretical
Peptide Content(N%) ?≥80.0%
Water Content(Karl Fischer)? ≤6.0%
Acetate Content(HPIC) ≤12.0%
MS(ESI) Consistent
Mass Balance? 95.0~105.0%
Description:
Oxytocin (Oxt) is a mammalian neurohypophysial hormone. Produced by the hypothalamus and stored and secreted by the posterior pituitary gland, oxytocin acts primarily as a neuromodulator in the brain.
Oxytocin plays an important role in the neuroanatomy of intimacy, specifically in sexual reproduction of both sexes, in particular during and after childbirth; Its name, meaning "swift childbirth", comes from Greek, oksys "swift" and, tokos "birth. " It is released in large amounts after distension of the cervix and uterus during labor, facilitating birth, maternal bonding, and, after stimulation of the nipples, lactation. Both childbirth and milk ejection result from positive feedback mechanisms.
Application:
Injected oxytocin analogues are used for labor induction and to support labor in case of difficult parturition. It has largely replaced ergometrine as the principal agent to increase uterine tone in acute postpartum hemorrhage. Oxytocin is also used in veterinary medicine to facilitate birth and to stimulate milk release. The tocolyticagent atosiban (Tractocile) acts as an antagonist of oxytocin receptors; This drug is registered in many countries to suppress premature labor between 24 and 33 weeks of gestation. It has fewer side effects than drugs previously used for this purpose (ritodrine).
Oxytocin is a hormone that’s produced in the hypothalamus and released into the bloodstream by the pituitary gland. Its main function is to facilitate childbirth, which is one of the reasons it is called the "love drug" or "love hormone."
Oxytocin both stimulates the muscles of the uterus to contract, and boosts the production of prostaglandins, which also increase uterine contractions. Women whose labor is slow to proceed are sometimes given oxytocin to speed the process. Once the baby is born, oxytocin helps to move milk from the ducts in the breast to the nipple, and foster a bond between mom and baby.
Our bodies also produce oxytocin when we’re excited by our sexual partner, and when we fall in love. That’s why it has earned the nicknames, "love hormone" and "cuddle hormone."
Low oxytocin levels have been linked to symptoms of depression, including postpartum depression. Researchers have been studying whether giving oxytocin in a pill or nasal spray might help to ease anxiety and depression, but so far the results have been disappointing. In part, that’s because it’s hard for this hormone to slip across the blood-brain barrier.
A more promising way to boost oxytocin naturally is with exercise. One study noted a jump in oxytocin levels measured in participants’ saliva after high-intensity martial arts training. Music also seems to have the ability to increase oxytocin levels, especially when people sing in a group, which adds the element of bonding.
Just the simple act of touch seems boost oxytocin release. Giving someone a massage, cuddling, making love, or giving someone a hug leads to higher levels of this hormone and a greater sense of well-being.
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