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99% Purity Benzyl Alcohol CAS 100-51-6 Liquid Aromatic Alcohol Intravenous Drugs

99% Purity Benzyl Alcohol CAS 100-51-6 Liquid Aromatic Alcohol Intravenous Drugs

  • 99% Purity Benzyl Alcohol CAS 100-51-6 Liquid Aromatic Alcohol Intravenous Drugs
  • 99% Purity Benzyl Alcohol CAS 100-51-6 Liquid Aromatic Alcohol Intravenous Drugs
  • 99% Purity Benzyl Alcohol CAS 100-51-6 Liquid Aromatic Alcohol Intravenous Drugs
  • 99% Purity Benzyl Alcohol CAS 100-51-6 Liquid Aromatic Alcohol Intravenous Drugs
99% Purity Benzyl Alcohol CAS 100-51-6 Liquid Aromatic Alcohol Intravenous Drugs
Product Details:
Place of Origin: China
Brand Name: Top Pharm
Certification: IOS 901
Model Number: 100-51-6
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Price: Negotiable
Packaging Details: As your requirments
Delivery Time: 3-6 working days
Payment Terms: T/T, Western Union, MoneyGram,bitcoin
Supply Ability: bulk stock
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Detailed Product Description
Purity: 99% Appearance: White Loose Lyophilized Powder.
Spec: 10G CAS: 100-51-6
MF: C7H8O MW: 108.14
High Light:

99% Purity Benzyl Alcohol Oil

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Benzyl Alcohol Semi Finished Steroids Oil

Benzyl Alcohol

Alias: Phenylmethanol; Benzyl alcohol 98+%; argopore-oh; Benzyl Alcohol BP; Benzenecarbinol; Benzenemethanol; Benzoyl alcohol; (hydroxymethyl)benzene; Hydroxytoluene; Phenylcarbinol; benzene;alcoolbenzylique;Bentalol;Benzoyl alcohol; Phenylmethyl alcohol
Purity : 99.0%
CAS Registry Number: 100-51-6
EINECS: 202-859-9
MF: C7H8O
MW: 108.14

 

Benzyl alcohol

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Benzyl alcohol
 
 
Names
Preferred IUPAC name
Phenylmethanol
Other names
Phenylcarbinol
Benzenemethanol
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.002.600 Edit this at Wikidata
EC Number
  • 202-859-9
E number E1519 (additional chemicals)
KEGG
RTECS number
  • DN3150000
UNII
Properties[1]
C7H8O
Molar mass 108.140 g·mol−1
Appearance Colorless liquid
Odor Slightly aromatic
Density 1.044 g/cm3
Melting point −15.2 °C (4.6 °F; 257.9 K)
Boiling point 205.3 °C (401.5 °F; 478.4 K)
3.50 g/100 mL (20 °C)
4.29 g/100 mL (25 °C)
Solubility in other solvents Soluble[vague] in benzene, methanol, chloroform, ethanol, ether, acetone
log P 1.10
Vapor pressure 0.18 kPa (60 °C)
Acidity (pKa) 15.40
−71.83·10−6 cm3/mol
1.5396
Viscosity 5.474 cP
1.67 D
Thermochemistry
217.8 J/(K·mol)
−352 kJ/mol
Pharmacology
P03AX06 (WHO)
Hazards
NFPA 704 (fire diamond)
Flash point 93 °C (199 °F; 366 K)
436 °C (817 °F; 709 K)
Explosive limits 1.3–13%
Lethal dose or concentration (LD, LC):
1250 mg/kg (rat, oral)
Safety data sheet (SDS) External MSDS
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Benzyl alcohol is an aromatic alcohol with the formula C6H5CH2OH. The benzyl group is often abbreviated "Bn" (not to be confused with "Bz" which is used for benzoyl), thus benzyl alcohol is denoted as BnOH. Benzyl alcohol is a colorless liquid with a mild pleasant aromatic odor. It is a useful solvent due to its polarity, low toxicity, and low vapor pressure. Benzyl alcohol has moderate solubility in water (4 g/100 mL) and is miscible in alcohols and diethyl ether. The anion produced by deprotonation of the alcohol group is known as benzylate or benzyloxide.

Natural occurrences

Benzyl alcohol is produced naturally by many plants and is commonly found in fruits and teas. It is also found in a variety of essential oils including jasmine, hyacinth and ylang-ylang.It is also found in castoreum from the castor sacs of beavers. Benzyl esters also occur naturally.

Preparation

Benzyl alcohol is produced industrially from toluene via benzyl chloride, which is hydrolyzed:

C6H5CH2Cl + H2O → C6H5CH2OH + HCl

Another route entails hydrogenation of benzaldehyde, a by-product of the oxidation of toluene to benzoic acid.[5]

For laboratory use, Grignard reaction of phenylmagnesium bromide (C6H5MgBr) with formaldehyde and the Cannizzaro reaction of benzaldehyde also give benzyl alcohol. The latter also gives benzoic acid, an example of an organic disproportionation reaction.

Reactions

Like most alcohols, it reacts with carboxylic acids to form esters. In organic synthesis, benzyl esters are popular protecting groups because they can be removed by mild hydrogenolysis.

Benzyl alcohol reacts with acrylonitrile to give N-benzylacrylamide. This is an example of a Ritter reaction:

C6H5CH2OH + NCCHCH2 → C6H5CH2N(H)C(O)CHCH2

Applications

Benzyl alcohol is used as a general solvent for inks, waxes, shellacs, paints, lacquers, and epoxy resin coatings. Thus it can be used in paint strippers, especially when combined with compatible viscosity enhancers to encourage the mixture to cling to painted surfaces.

It is a precursor to a variety of esters and ethers, used in the soap, perfume, and flavor industries. E.g. benzyl benzoate, benzyl salicylate, benzyl cinnamate, dibenzyl ether, benzyl butyl phthalate.

It can be used as a local anesthetic, especially with epinephrine.

As a dye solvent, it enhances the process of dying wool, nylon, and leather.

Use in health care

Benzyl alcohol is used as a bacteriostatic preservative at low concentration in intravenous medications, cosmetics, and topical drugs. Some caution is necessary if a high percent of Benzyl alcohol is used as benzaldehyde arises from benzyl alcohol when used as preservative in an injectable formulation solution. 

Benzyl alcohol, sold under the brand name Ulesfia, was approved by the U.S. Food and Drug Administration (FDA) in 2009, as a 5% solution for the treatment of head lice in people 6 months of age and older. It affects the louse's spiracles, preventing them from closing. These then become clogged with water or mineral oil or other matter and cause the insect to die from asphyxiation.

Benzyl alcohol is used effectively for treating lice infestations as the active ingredient in lotion shampoo with 5% benzyl alcohol.

Contact dermatitis

 
Illustration of allergic contact dermatitis

Benzyl alcohol is an ingredient used in the manufacture of soaps, topical creams, skin lotions, shampoos, and facial cleansers and is popular due to its anti-bacterial and anti-fungal properties. It is a common ingredient in a variety of household products and can cause severe allergic contact dermatitis in a significant percentage of the population.

Safety

Benzyl alcohol has low acute toxicity with an LD50 of 1.2 g/kg in rats.[5] It oxidizes rapidly in healthy individuals to benzoic acid, conjugated with glycine in the liver, and excreted as hippuric acid. Very high concentrations can result in toxic effects including respiratory failure, vasodilation, hypotension, convulsions, and paralysis.

Benzyl alcohol is toxic to neonates and is associated with the gasping syndrome.

Benzyl alcohol is severely toxic and highly irritating to the eye.Pure benzyl alcohol produces corneal necrosis.

Benzyl alcohol is not considered to be a carcinogen, and no data are available regarding teratogenic or reproductive effects.

 

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99% Purity Benzyl Alcohol CAS 100-51-6 Liquid Aromatic Alcohol Intravenous Drugs 12

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