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99% Purity Tetracaine Hydrochloride CAS 136-47-0 White Powder Local Anesthetic Antipruritic Agent

99% Purity Tetracaine Hydrochloride CAS 136-47-0 White Powder Local Anesthetic Antipruritic Agent

  • 99% Purity Tetracaine Hydrochloride CAS 136-47-0 White Powder Local Anesthetic Antipruritic Agent
  • 99% Purity Tetracaine Hydrochloride CAS 136-47-0 White Powder Local Anesthetic Antipruritic Agent
  • 99% Purity Tetracaine Hydrochloride CAS 136-47-0 White Powder Local Anesthetic Antipruritic Agent
  • 99% Purity Tetracaine Hydrochloride CAS 136-47-0 White Powder Local Anesthetic Antipruritic Agent
99% Purity Tetracaine Hydrochloride CAS 136-47-0 White Powder Local Anesthetic Antipruritic Agent
Product Details:
Place of Origin: China
Brand Name: Top Pharm
Certification: IOS 901
Model Number: 136-47-0
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Price: Negotiable
Packaging Details: As your requirments
Delivery Time: 3-6 working days
Payment Terms: T/T, Western Union, MoneyGram,bitcoin
Supply Ability: bulk stock
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Detailed Product Description
Purity: 99% Appearance: White Loose Lyophilized Powder.
Spec: 10G CAS: 136-47-0
MF: C15H25ClN2O2 MW: 300.827
High Light:

99% Purity Tetracaine Hydrochloride Powder

,

Local Anesthetic Antipruritic Tetracaine Hydrochloride

Tetracaine Hydrochloride
 
Chemical Names: Tetracaine hydrochloride; Tetracaine HCl; Butethanol; Butylocaine; Anethain
CAS number: 136-47-0;
Molecular Formula: C15H25ClN2O2
Molecular Weight: 300.827 g/mol


 

 

Tetracaine (also known as amethocaine) is a local anesthetic of the ester anesthetic group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.[1]

Tetracaine is the T in TAC, a mixture of 5 to 12% tetracaine, 0.05% adrenaline, and 4 or 10% cocaine hydrochloride used in ear, nose, and throat surgery and in the emergency department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.


1 Pharmacodynamic properties
Tetracaine hydrochloride is used as a local anaesthetic which acts by reversibly blocking the propagation and conduction of nerve impulses along nerve axons. Tetracaine stabilises the nerve membrane, preventing the increase in sodium permeability necessary for the production of an action potential.
5.2 Pharmacokinetic properties
Tetracaine is a weak base (pKa 8.5), therefore, significant changes in the rate of ionised lipid soluble drug uptake may occur with changes in the acid base balance.
In vitro studies have shown that tetracaine has a high affinity for melanin, therefore, differences in duration of action may be expected between deeply pigmented eyes and less pigmented eyes.
The primary site of metabolism for tetracaine is the plasma. Pseudocholinesterases in the plasma hydrolyse tetracaine to 4-aminobenzoic acid. Unmetabolised drug is excreted in the urine.
5.3 Preclinical safety data
No adverse safety issues were detected during the development of this formulation. The active ingredient is well established in clinical ophthalmology.

 

Tetracaine hydrochloride

PubChem CID 8695
Structure
Tetracaine hydrochloride_small.png
Tetracaine hydrochloride_3D_Structure.png
Chemical Safety

 

Acute Toxic
Irritant
Health Hazard

 

Molecular Formula C15H25ClN2O2
Synonyms

Tetracaine hydrochloride

136-47-0

Tetracaine HCl

Amethocaine hydrochloride

Butethanol

Molecular Weight 300.82
Parent Compound 99% Purity Tetracaine Hydrochloride CAS 136-47-0 White Powder Local Anesthetic Antipruritic Agent 5CID 5411 (Tetracaine)
Component Compounds

99% Purity Tetracaine Hydrochloride CAS 136-47-0 White Powder Local Anesthetic Antipruritic Agent 6CID 313 (Hydrochloric Acid)

99% Purity Tetracaine Hydrochloride CAS 136-47-0 White Powder Local Anesthetic Antipruritic Agent 5CID 5411 (Tetracaine)

Dates
  • Modify

    2022-10-14

  • Create

    2005-06-24

 

1.12D Structure

 
Chemical Structure Depiction
Tetracaine hydrochloride.png

 

Polypeptide Hormones we supply
Melanotan II CAS 121062-08-6 timulate the body's tanning response
Selank CAS 129954-34-3 help enhance mental sharpness,enhance memory
DSIP CAS 62568-57-4 Delta sleep-inducing peptide, abbreviated DSIP
Gonadotropin CAS 71447-49-9 Mainly used for prostate cancer
Tesamorelin CAS 218949-48-5 used in the treatment of HIV-associated lipodystrophy
Triptorelin CAS 57773-63-4 used as the acetate or pamoate salts
HG 176-191   the fat-reducing effects
Pentadecapeptide BPC 157 CAS 137525-51-0 increasing lean muscular tissue mass, reducing fat
TB500 CAS 77591-33-4 oincrease muscle growth
Oxytocin CAS 50-56-6 used for stimulation of uterus contractions
Sermorelin CAS 86168-78-7 Increases the development of lean body mass
Hexarelin CAS 140703-51-1 the treatment of growth hormone secretion deficiency
Ipamorelin CAS 170851-70-4 a selective growth hormone secretagogue
Melanotan 1 CAS 75921-69-6 endogenous melanocortine peptide
MGF   used by bodybuilders and athletes
PEG-MGF   cause site specific muscle growth
CJC-1295 Without DAC CAS 863288-34-0 increasing binding affinity to the GHRH receptors
CJC-1295 with DAC CAS 863288-34-0 improved physique and sense of well being
PT-141   increase libido effects of both men and women
GHRP-2 CAS 158861-67-7 growth hormone stimulation
GHRP-6 CAS 87616-84-0 Increase in strength,Muscle mass,Body fat loss
Tb-500 CAS 77591-33-4 increases in endurance,strength and muscle growth

 

 

 

 

 

 

99% Purity Tetracaine Hydrochloride CAS 136-47-0 White Powder Local Anesthetic Antipruritic Agent 9

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