TOP PHARM CO.,LIMITED
|Place of Origin:||China|
|Brand Name:||Top Pharm|
|Minimum Order Quantity:||10g|
|Packaging Details:||As your requirments|
|Delivery Time:||3-6 working days|
|Payment Terms:||T/T, Western Union, MoneyGram,bitcoin|
|Supply Ability:||bulk stock|
|Purity:||99%||Appearance:||White Loose Lyophilized Powder.|
Human Growth Hormone Hexarelin Peptide,
Bodybuilding Hexarelin Powder
Product Name Hexarelin
Cas No. 140703-51-1
Molecular Formula C47H58N12O6
Molecular Weight 887.0
Appearance White Powder
IR spectrum in accordance
Hexarelin is a very powerful peptide GH secretagogue (also
referred to as GHRP). Hexarelin is characterized by having a
longer terminal half-life (approximately 70 min) than most other
hormone peptides and is extremely effective at releasing GH .
This long half-life is inherent with peptides that have been
modified by replacement of the naturally occurring l amino acids
for thed-configuration. The pharmacokinetics of hexarelin
correlates well with the pharmacodynamic findings reported by
Deghenghi et al. (1994) who observed that in the adult male rat,
GH peak levels were apparent 20 min after the s.c. administration
of hexarelin. The authors observed that GH secretion induced by
hexarelin was prompt and sustained as it was still highly
stimulated at 30 min.?
Growth hormone secretagogues (GHS) are a class of small synthetic peptides that stimulate growth hormone (GH) release through binding to the growth hormone secretagogue receptor (GHSR) 1a. Moreover, GHSR 1a is a G-protein-coupled receptor originally identified in the hypothalamus and pituitary, and later recognized as the receptor for the endogenous hormone ghrelin. The peripheral distribution of GHSR 1a in the heart, adrenals, fat, prostate, bone, and digestive tract has supported physiological roles of GHSs and ghrelin independent of GH release and neuroendocrine stimulation. For example, GH-independent effects on orexigenic properties, fat metabolism, immune, gastrointestinal, and cardiovascular activities have been reported for GHSs and ghrelin
Previous studies have revealed that ghrelin administration can improve cardiac function in rats and patients with chronic heart failure, as indicated by increased left ventricle ejection fraction (LVEF), cardiac output, and exercise capacity. In rodents with acute myocardial infarction (MI), ghrelin administration prevented malignant arrhythmias and reduced mortality in the acute phase, while improving left ventricle (LV) dysfunction and attenuating cardiac remodeling in the subacute phase.– However, ghrelin is an unstable natural peptide that is transformed and degraded, which limits its clinical use. The GHS hexarelin is a chemically stable and potent synthetic hexapeptide that can be administered orally, making it a potential alternative to ghrelin. It is comparable to ghrelin with respect to the half-maximal effective concentration for their common receptor, GHSR 1a; although the cardiac action of hexarelin was reported to be mediated in part by GHSR 1a and largely by activation of the CD36 receptor, in isolated working hearts. In this concise review, we discuss the current evidence for the cardiovascular action of hexarelin.
|Fast Delivery||Delivery within 24 hours upon receipt of your payment|
|Quality||Quality can be promised. Hot sell to Worldwide|
|Payment Terms||T/T Bank Transfer, Western Union, Paypal, Bitcoin and MoneyGram Available|
|Sample||Sample available at any time|
|Package||Professional packing with professional materials|
Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC ,
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.
Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price.
Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
we accept bank transfer,Western Union and
Q6:How long does it take to the goods arrived ?
A:It is Depending on your location.For small order,please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.For mass order,please allow 5-8 days by Air, 20-35 days by Sea.
Q7:Do you have any reshipment policy ?
we have good after-sale service and re-shipment policy if the parcel lose
Our long association with our clients has brought great benefits
We always take the upmost care in the packaging of our products
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible will seize a small number of packages.
In this circumstance we promise reship free to establish long term relationship
Q8:Can I get a sample?
A: Of course. For most products we can provide you a free sample, while the shipping cost shouldundertake by your side.
Contact Person: Baron