TOP PHARM CO.,LIMITED
Place of Origin: | China |
Brand Name: | Top Pharm |
Certification: | IOS 901 |
Model Number: | 40077-57-4 |
Minimum Order Quantity: | 10g |
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Price: | Negotiable |
Packaging Details: | As your requirments |
Delivery Time: | 3-6 working days |
Payment Terms: | T/T, Western Union, MoneyGram,bitcoin |
Supply Ability: | bulk stock |
Appearance: | White Powder | Purity: | 99% |
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CAS NO: | 40077-57-4 | Molecular Formula: | C147H238N44O42S |
Molecular Weight: | 3325.87 | ||
High Light: | Aviptadil Acetate Intestinal Peptide,Calbiochem Body Building Peptides,CAS 40077-57-4 Aviptadil Acetate |
Product Name Aviptadil Acetate
Sequence His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2
Cas No. 40077-57-4
Molecular Formula C147H238N44O42S
Molecular Weight 3325.87
Purity (HPLC) 98.0%
Appearance White powder
Single Impurity(HPLC) 1.0%
Amino Acid Composition 10% of theoretical
Peptide Content(N%) 80%(by %N)
Water Content(Karl Fischer) 6.0%
Acetate Content(HPIC) 15.0%
MS(ESI)
Mass Balance 95.0~105.0%
SARS-CoV-2 virus infection is known to cause Lung Injury that begins as dyspnea and exercise intolerance, but may rapidly progress to Critical COVID-19 with Respiratory Failure and the need for noninvasive or mechanical ventilation. Mortality rates as high as 80% have been reported among those who require mechanical ventilation, despite best available intensive care.
Patients with severe COVID-19 by FDA definition who have not developed respiratory failure be treated with nebulized ZYESAMI™ (aviptadil acetate, a synthetic version of Vasoactive Intestinal Polypeptide (VIP)) 100 μg 3x daily plus Standard of Care vs. placebo + Standard of Care using an FDA 501(k) cleared mesh nebulizer.
The primary outcome will be progression in severity of COVID-19 (i.e. critical OR severe progressing to critical) over 28 days. Secondary outcomes will include blood oxygenation as measured by pulse oximetry, dyspnea, exercise tolerance, and levels of TNFα IL-6 and other cytokines.
Brief Summary: SARS-CoV-2 virus infection is known to cause Lung Injury that begins as dyspnea and exercise intolerance, but may rapidly progress to Critical COVID-19 with Respiratory Failure and the need for noninvasive or mechanical ventilation. Mortality rates as high as 80% have been reported among those who require mechanical ventilation, despite best available intensive care. Patients with severe COVID-19 by FDA definition who have not developed respiratory failure be treated with nebulized ZYESAMI™ (aviptadil acetate, a synthetic version of Vasoactive Intestinal Polypeptide (VIP)) 100 μg 3x daily plus Standard of Care vs. placebo + Standard of Care using an FDA 501(k) cleared mesh nebulizer. The primary outcome will be progression in severity of COVID-19 (i.e. critical OR severe progressing to critical) over 28 days. Secondary outcomes will include blood oxygenation as measured by pulse oximetry, dyspnea, exercise tolerance, and levels of TNFα IL-6 and other cytokines.
Aviptadil acetate is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil acetate induces pulmonary vasodilation and inhibits vascular SMCs proliferation, platelet aggregation. Aviptadil acetate can be used for the research of pulmonary fibrosis, pulmonary arterial hypertension (PAH) and SARS-CoV-2 caused respiratory failure, et al.
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Our Service | |
Fast Delivery | Delivery within 24 hours upon receipt of your payment |
Quality | Quality can be promised. Hot sell to Worldwide |
Payment Terms | T/T Bank Transfer, Western Union, Paypal, Bitcoin and MoneyGram Available |
Sample | Sample available at any time |
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+86 18702784137 |
Package | Professional packing with professional materials |
Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC ,
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.
Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price.
Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
we accept bank transfer,Western Union and
Q6:How long does it take to the goods arrived ?
A:It is Depending on your location.For small order,please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.For mass order,please allow 5-8 days by Air, 20-35 days by Sea.
Q7:Do you have any reshipment policy ?
we have good after-sale service and re-shipment policy if the parcel lose
Our long association with our clients has brought great benefits
We always take the upmost care in the packaging of our products
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible will seize a small number of packages.
In this circumstance we promise reship free to establish long term relationship
Q8:Can I get a sample?
A: Of course. For most products we can provide you a free sample, while the shipping cost shouldundertake by your side.
Contact Person: Anne
Tel: +8618702784137