Tamoxifen Citrate
1. CAS No:54965-24-1
2. Molecular Formula: C26H29NO.C6H8O7
3. Assay: 97.0%~103.0%
4. Appearance: White crystalline powder.
5. Usage: the goods to anti-estrogen fertility inducer, the objects in dysfunctional uterine bleeding, polycystic ovary, menstrual disorders and drug-induced amenorrhea and other gynecologic diseases;It is used as a first line defense against breast cancer.
How to use Tamoxifen CITRATE
Read the Medication Guide provided by your pharmacist before you start using tamoxifen and each time you get a refill. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth with or without food, usually once or twice daily for 5 years, or as directed by your doctor. Daily dosages greater than 20 milligrams are usually divided in half and taken twice a day, in the morning and evening, or as directed by your doctor. If you are using the liquid, measure the dose carefully using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
Dosage is based on your medical condition and response to treatment. The duration of treatment to prevent cancer from returning may be between 5 to 10 years, depending on your medical condition and response to treatment.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.
Description:
It has been established that breast cancer is responsible for more than 13% of all deaths in women when it comes to different types of cancer. It is therefore a condition that needs to be battled against with all means necessary. Of course, the best way to treat breast cancer is to prevent it by regular checkups that can even be done at home, by checking the breast tissue for any unusual lumps or growths. The good news is that if breast cancer is noticed in the early stages, the survival rate is very high. In some cases, surgery is required, but in the majority of cases, the medications will do the trick. One of the drugs most commonly used in treating breast cancer is Nolvadex, a drug that is metabolized into hydroxytamoxifen which prevents the action of estrogen that is most commonly responsible for the growth of breast cancer. The way in which Nolvadex works could be best described as a broken key. Namely, this medication, or more precisely, its metabolite binds to the estrogen receptors in cancer cells, thus preventing anything else (estrogen) from binding to the receptors. This way, Nolvadex prevents the growth of cancer and helps in treating it. Due to its effect on estrogen receptors, there are other uses for Nolvadex, such as in treating infertility in female patients who are suffering from anovulatory disorders. Another condition that can be treated by Nolvadex is gynecomastia, as well as a rare condition known as retroperitoneal fibrosis. Some other properties of Nolvadex make it a useful tool in treating manic episodes in patients suffering from bipolar disorder and it is also being tried for preventing angiogenesis.
Side Effects
See also Warning section.
Hot flashes, nausea, leg cramps, muscle aches, hair thinning, headache, and numb/tingling skin may occur. A loss of sexual ability/interest may occur in men. If these effects persist or worsen, notify your doctor promptly.
Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: vision changes (such as blurred vision), eye pain, easy bruising/bleeding, mental/mood changes, swelling of ankles/feet, unusual tiredness, signs of infection (such as fever, persistent sore throat), signs of liver disease (such as nausea/vomiting that doesn't stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine).
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
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