CAS 137525-51-0 5mg/Vial Growth Hormone Bodybuilding BPC 157White Lyophilized Powder White loose lyophilized powder.

pentadecapeptide BPC 157

Alias: Booly Protection Compound 15, Pentadecapeptide, BPC 157

CAS: 137525-51-0

Sequence: Gly-Glu-Pro-Pro-Pro-Gly- Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

MF: C62H98N16O22

MW: 1419.53552

Purity: 99%

Appearance: White Lyophilized Powder

Place of Origin: China

Standard: USP

Certification: SGS

Method of Analysis: HPLC

BPC 157 Description:

1. Pentadecapeptide BPC 157, composed of 15 amino acids, is a partial sequence of body protection compound (BPC) that is discovered in and isolated from human gastric juice. Experimentally it has been demonstrated to accelerate the healing of many different wounds, including transected rat Achilles tendon.

2. This study was designed to investigate the potential mechanism of BPC 157 to enhance healing of injured tendon. The outgrowth of tendon fibroblasts from tendon explants cultured with or without BPC 157 was examined. Results showed that BPC 157 significantly accelerated the outgrowth of tendon explants.

3. Cell proliferation of cultured tendon fibroblasts derived from rat Achilles tendon was not directly affected by BPC 157 as evaluated by MTT assay. However, the survival of BPC 157-treated cells was significantly increased under the H(2)O(2) stress.

BPC 157 Applications:

1. Stable gastric pentadecapeptide BPC 157 (GEPPPGKPADDAGLV, M.W. 1419) may be the new drug stable in human gastric juice, effective both in the upper and lower GI tract, and free of side effects.

2. BPC 157, in addition to an antiulcer effect efficient in therapy of inflammatory bowel disease (IBD) (PL 14736) so far only tested in clinical phase II, has a very safe profile, and exhibited a particular wound healing effect.

3. It also has shown to interact with the NO-saystem, providing endothelium protection and angiogenic effect, even in severely impaired conditions (i.e., it stimulated expression of early growth response 1 gene responsible for cytokine and factor generation and early extracellular matrix (collagen) formation (but also its repressor nerve factor 1- A binding protein-2)), important to counteract severe complications of advanced and poorly controlled IBD.

BPC 157 Dosages:

Experiments saw results with oral, peritoneal, and site injections. 10 micrograms per kg was the dose in rats for these results. This means oral or injection makes no difference, with a tiny bit of this healing becomes a whole lot easier

BPC 157 Storage :

Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below -18° C.
pentadecapeptide BPC 157essential fragment of organoprotective gastric juice peptide BPCwrithing (acetic acid/magnesium sulphate)tail pinching testhot-plate testinflammatory/non-inflammatory, indirect/direct nociceptioncapsaicinallodyniacapsaicin-sensitive somatosensory neurons integrity/protection.