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C19H30O2 Androsterone 1 Dehydroepiandrosterone CAS 53-41-8

C19H30O2 Androsterone 1 Dehydroepiandrosterone CAS 53-41-8

  • C19H30O2 Androsterone 1 Dehydroepiandrosterone CAS 53-41-8
  • C19H30O2 Androsterone 1 Dehydroepiandrosterone CAS 53-41-8
C19H30O2 Androsterone 1 Dehydroepiandrosterone CAS 53-41-8
Product Details:
Place of Origin: China
Brand Name: Top Pharm
Certification: IOS 901
Model Number: 53-41-8
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Price: Negotiable
Packaging Details: As your requirments
Delivery Time: 3-6 working days
Payment Terms: T/T, Western Union, MoneyGram,bitcoin
Supply Ability: bulk stock
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Detailed Product Description
Appearance: White Loose Lyophilized Powder. Purity: 99%
Spec: 10G MF: C19H30O2
MW: 290.44
High Light:

Androsterone 1 Dehydroepiandrosterone

,

C19H30O2 1 Dehydroepiandrosterone

,

CAS 53-41-8 1 Dehydroepiandrosterone

Product Name: Androsterone 1-Dehydroepiandrosterone
Synonyms: 3α-Hydroxy-5α-androstan-17-one;5α-Androstan-3α-ol-17-one
CAS No.: 53-41-8
M.F.: C19H30O2
M.W.: 290.44
Assay: 98%
Melting Point: 181-184℃
Appearance: White or white crystalline powder

 

 

 

DHEA is one of the most abundant steroid hormones in the human body. It is produced by the adrenal glands, the gonads, and the brain. It is normally found in the form ofdehydroepiandrosterone sulfate (DHEAS). The body holds DHEAS in reserve and converts it to specific hormones when needed.

 

Tetrahydrogestrinone (THG) is a steroid recently identified to be misused as doping agent. However, the knowledge on functions of this substance in humans or animal models is rather limited. Therefore, it was our aim to further characterize the pharmacological profile of THG and identify potential adverse side effects. THG was synthesized, the purity was confirmed and its biological activity was tested. The potency of THG to transactivate AR dependent reporter gene expression was two orders of magnitude lower compared to dihydrotestosterone. THG binds with high affinity but unselective to the androgen (AR), progesterone (PR), glucocorticoid (GR) and mineralocorticoid (MR) receptor. Treatment of orchiectomised rats with THG resulted in a stimulation of prostate, seminal vesicle and levator ani muscle, indicating androgenic and anabolic properties. In the liver THG, in contrast to testosteronepropionate (TP), down regulates the expression of the GR dependent tyrosine aminotransferase gene (TAT). In summary, our results demonstrate that THG is not a specific AR agonist. THG exhibits a high binding affinity to all tested steroid hormone receptors and binds with highest affinity to the GR. Our in vivo data are indicative of an anabolic and androgenic potency of THG, but the repression of TAT demonstrates that THG also interferes with the glucocorticoid hormone system. Therefore, it is conceivable that an intake will result in adverse side effects.

 

 

Uses & Effectiveness ?

 

Likely Effective for

  • Thinning of vaginal tissue (vaginal atrophy). The walls of the vagina can become thinner after menopause. This can cause pain during sex. Using vaginal inserts containing DHEA can reduce pain during sex by up to 15% after menopause. A prescription DHEA product is available for this condition.

Possibly Effective for

  • Aging skin. Some research shows that taking DHEA by mouth or applying it to the skin might improve skin appearance after menopause and in people over the age of 60 years.
  • Depression. Some research shows that taking 30-500 mg of DHEA by mouth daily improves symptoms of depression. Lower doses do not seem to help. Some experts recommend DHEA for depression if more common medications don't work.
  • Inability to become pregnant within a year of trying to conceive (infertility). Most research shows that taking DHEA for 2 to 3 months before in-vitro fertilization (IVF) might improve the chances of pregnancy and having a baby. However, other research shows that taking DHEA does not seem to prevent miscarriage after IVF.

Possibly Ineffective for

  • Aging. Taking DHEA daily for up to 2 years does not seem to improve body shape, bone strength, muscle strength, or quality of life in people older than 60 who have low DHEA levels.

Interactions ?

Moderate Interaction

Be cautious with this combination

  • Anastrozole (Arimidex) interacts with DHEA

    The body changes DHEA to estrogen in the body. Anastrozole (Arimidex) is used to help decrease estrogen in the body. Taking DHEA along with anastrozole (Arimidex) might decrease the effectiveness of anastrozole (Arimidex). Do not take DHEA if you are taking anastrozole (Arimidex).

  • Exemestane (Aromasin) interacts with DHEA

    The body changes DHEA to estrogen in the body. Exemestane (Aromasin) is used to help decrease estrogen in the body. Taking DHEA along with exemestane (Aromasin) might decrease the effectiveness of exemestane (Aromasin). Do not take DHEA if you are taking exemestane (Aromasin).

  • Fulvestrant (Faslodex) interacts with DHEA

    Some types of cancer are affected by hormones in the body. Estrogen-sensitive cancers are cancers that are affected by estrogen levels in the body. Fulvestrant (Faslodex) is used for this type of estrogen cancer. DHEA might increase estrogen in the body and decrease the effectiveness of fulvestrant for treating cancer. Do not take DHEA if you are taking fulvestrant

 

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C19H30O2 Androsterone 1 Dehydroepiandrosterone CAS 53-41-8 0

 

 

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