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136-47-0 Hydrochloride Pain Killer , Injectable Local Anesthetics 99% Purity

136-47-0 Hydrochloride Pain Killer , Injectable Local Anesthetics 99% Purity

  • 136-47-0 Hydrochloride Pain Killer , Injectable Local Anesthetics 99% Purity
  • 136-47-0 Hydrochloride Pain Killer , Injectable Local Anesthetics 99% Purity
136-47-0 Hydrochloride Pain Killer , Injectable Local Anesthetics 99% Purity
Product Details:
Place of Origin: China
Brand Name: Top Pharm
Certification: IOS 901
Model Number: 136-47-0
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Price: Negotiable
Packaging Details: As your requirments
Delivery Time: 3-6 working days
Payment Terms: T/T, Western Union, MoneyGram,bitcoin
Supply Ability: bulk stock
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Detailed Product Description
Appearance: White Or White Crystalline Powder Other Names: Tetracaine HCl
Purity: 99% Molecular Weight: 300.827
Molecular Formula: C15H25ClN2O2
High Light:

lidocaine local anesthetic

,

lidocaine hydrochloride oral

99% purity local anesthetics Pharmaceutical raw materials Tetracaine Hydrochloride/Tetracaine HCl CAS 136-47-0
 
Chemical Names: Tetracaine hydrochloride; Tetracaine HCl; Butethanol; Butylocaine; Anethain
CAS number: 136-47-0;
Molecular Formula: C15H25ClN2O2
Molecular Weight: 300.827 g/mol
 
Tetracaine (also known as amethocaine) is a local anesthetic of the ester anesthetic group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
 
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.[1]
 
Tetracaine is the T in TAC, a mixture of 5 to 12% tetracaine, 0.05% adrenaline, and 4 or 10% cocaine hydrochloride used in ear, nose, and throat surgery and in the emergency department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.
 
 
1 Pharmacodynamic properties
Tetracaine hydrochloride is used as a local anaesthetic which acts by reversibly blocking the propagation and conduction of nerve impulses along nerve axons. Tetracaine stabilises the nerve membrane, preventing the increase in sodium permeability necessary for the production of an action potential.
5.2 Pharmacokinetic properties
Tetracaine is a weak base (pKa 8.5), therefore, significant changes in the rate of ionised lipid soluble drug uptake may occur with changes in the acid base balance.
In vitro studies have shown that tetracaine has a high affinity for melanin, therefore, differences in duration of action may be expected between deeply pigmented eyes and less pigmented eyes.
The primary site of metabolism for tetracaine is the plasma. Pseudocholinesterases in the plasma hydrolyse tetracaine to 4-aminobenzoic acid. Unmetabolised drug is excreted in the urine.
5.3 Preclinical safety data
No adverse safety issues were detected during the development of this formulation. The active ingredient is well established in clinical ophthalmology.

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136-47-0 Hydrochloride Pain Killer , Injectable Local Anesthetics 99% Purity 0

 

 

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Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.

Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC ,
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.

Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.

Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price.

Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
we accept bank transfer,Western Union and Money Gram

Q6:How long does it take to the goods arrived ?
A:It is Depending on your location.For small order,please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.For mass order,please allow 5-8 days by Air, 20-35 days by Sea.

Q7:Do you have any reshipment policy ?
we have good after-sale service and re-shipment policy if the parcel lose
Our long association with our clients has brought great benefits
We always take the upmost care in the packaging of our products
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible will seize a small number of packages.
In this circumstance we promise reship free to establish long term relationship

Q8:Can I get a sample?
A: Of course. For most products we can provide you a free sample, while the shipping cost shouldundertake by your side.

 

 

 

 

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Tel: +86 15377023931

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